Living with depression despite taking an antidepressant?

See if you may qualify for a local Phase III clinical research study for adults with Major Depressive Disorder (MDD).

You may qualify if you:

• Are 18 years or older
• Have been diagnosed with Major Depressive Disorder
• Are currently taking an antidepressant
• Continue experiencing symptoms of depression

Why Consider Participating?

If you qualify, you may receive:

• Study-related care at no cost
• An investigational study medication or placebo during the initial study period
• Care from experienced clinical research professionals
• Regular health evaluations throughout the study
• Compensation for time and travel

About the Study

This Phase III clinical research study is evaluating an investigational medication used in combination with a participant’s current antidepressant.

During the initial study period, participants are randomly assigned to receive either the investigational medication or placebo. Neither participants nor the study team will know which treatment has been assigned during this portion of the study.

Eligible participants may have the opportunity to continue into an optional long-term extension after completing the initial study period.

What to Expect

The initial study treatment lasts approximately 6 weeks.

Eligible participants may have the opportunity to continue into an optional extension lasting approximately one year

Study visits may include:

• Depression symptom evaluations
• Physical examinations
• Blood and urine laboratory testing
  Electrocardiograms (ECGs)
• Vital signs
• Medication review
• Safety monitoring

Study-related procedures are provided at no cost.

Frequently Asked Questions

Will I continue taking my antidepressant?

Yes. Participants remain on their current eligible antidepressant throughout the initial study period.

Will everyone receive the investigational medication?

No. Participants are randomly assigned to receive either investigational medication or placebo during the double-blind portion of the study.

Eligible participants may later enter an optional open-label extension.

What is placebo?

A placebo looks like the investigational medication but contains no active medication. Placebos help researchers compare treatments fairly and accurately.

Will I be paid?

Compensation for time and travel is available. Ask the study team for details.

Can I leave the study?

Yes. Participation is completely voluntary, and you may withdraw at any time.

Ready to Learn More?

Find out whether you may qualify for this depression clinical research study.

See If You May Qualify.